Vitamin B5 (Calcium D Pantothenate)
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Vitamin B5 Powder (Calcium D Pantothenate) also known as Cal-Pan
Here at Arndale Ingredients we supply Vitamin B5 powder (Calcium D Pantothenate, Cal-Pan) to some of the largest food and beverage companies in the UK. Our Vitamin B5 Powder(Calcium D Pantothenate Cal-Pan) is packed in 25kg boxes. Our Vitamin B5 Powder(Calcium D Pantothenate, Cal-Pan) meets both kosher and Halal requirements.
Calcium Pantothenate - Vitamin B5 is known to be important in helping to maintain our immune systems also in helping to maintain a healthy heart and cholesterol levels. Helps release energy from food - needed for healthy growth. A prolonged release formula.
Small quantities of Vitamin B5 (Calcium D Pantothenate) are found in most foods. The major food source Vitamin B5 (Calcium D Pantothenate) is in meats, although the concentration found in food animals' muscles is only about half that in humans' muscles. Whole grains are another good source of the vitamin, but milling often removes much of the Vitamin B5 (Calcium D Pantothenate), as it is found in the outer layers of whole grains. Vegetables, such as broccoli and avocados, also have an abundance of the acid. In animal feeds, the most important sources of the vitamin are rice, wheat brans, alfalfa, peanut meal, molasses, yeasts, and condensed fish solutions. The most significant sources of pantothenic acid in nature are coldwater fish ovaries and royal jelly. A recent study also suggests that gut bacteria in humans can generate Vitamin B5 (Calcium D Pantothenate), but this has not yet been proven.
The derivative of pantothenic acid, pantothenol, is a more stable form of the vitamin and is often used as a source of the vitamin in multivitamin supplements. Another common supplemental form of the vitamin is calcium pantothenate. Calcium pantothenate is often used in dietary supplements because as a salt, it is more stable than pantothenic acid in the digestive tract allowing for better absorption. Possible benefits of supplementation: Doses of 2g/day of calcium pantothenate may reduce the duration of morning stiffness, a degree of disability, and pain severity in rheumatoid arthritis patients. Although the results are inconsistent, supplementation may improve oxygen utilization efficiency and reduce lactic acid accumulation in athletes.
Testicular Torsion can severely affect fertility if it occurs. One study on a rat model indicated that a treatment of 500 mg of dexpanthenol/kg body weight 30 minutes prior to detorsion can greatly decrease the risk of infertility after torsion. Vitamin B5 (Calcium D Pantothenate) has the ability to spare reduced levels. Reactive oxygen species play a role in testicular atrophy, which the glutathione can 'fight' against.
Vitamin B5 (Calcium D Pantothenate) derivatives, panthenol, phosphopantetheine and pantethine, have also been seen to improve the lipid profile in the blood and liver. In a mouse model, they injected 150 mg of the derivative/kg body weight. All three derivatives were able to effectively lower low-density lipoprotein (LDL) as well as triglyceride (TG) levels, panthenol was able to lower total cholesterol and pantethine was able to lower LDL-cholesterol in the serum. The decrease in LDL-cholesterol is significant, as it will decrease the risk of heart attack and stroke. In the liver, panthenol was the most effective, as it lowered TG, T-chol, free cholesterol and cholesterol-ester levels.
A study in 1999 showed that Vitamin B5 (Calcium D Pantothenate) has an effect on wound healing in vitro. Wiemann and Hermann found that cell cultures with a concentration of 100Î¼g/mL calcium D-pantothenate increased migration, and the fibres ran directionally with several layers, whereas the cell cultures without pantothenic acid healed in no orderly motion, and with fewer layers. Cell proliferation or cell multiplication was found to increase with Vitamin B5 (Calcium D Pantothenate) supplementation. Finally, there were increased concentrations of two proteins, both of which have still to be been identified, that was found in the supplemented culture, but not on the control. Further studies are needed to determine whether these effects will stand in vivo.
Mouse models identified skin irritation and loss of hair colour as possible results of severe Vitamin B5 (Calcium D Pantothenate) deficiency. As a result, the cosmetic industry began adding pantothenic acid to various cosmetic products, including shampoo. These products, however, showed no benefits in human trials. Despite this, many cosmetic products still advertise pantothenic acid additives.
No dietary requirement for Vitamin B5 (Calcium D Pantothenate) has been established as the synthesis of pantothenic acid by ruminal microorganisms appears to be 20 to 30 times more than dietary amounts. Net microbial synthesis of pantothenic acid in the rumen of steer calves has been estimated to be 2.2 mg/kg of digestible organic matter consumed per day. The degradation of dietary intake of pantothenic acid is considered to be 78%. Supplementation of Vitamin B5 (Calcium D Pantothenate) at 5 to 10 times theoretic requirements did not improve the performance of feedlot cattle.
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